SUN-LB62 Differential Regulation of 22 kDa and 20 kDa Growth Hormone Isoforms in Response to Acute Glucose Load and Moderate Intensity Exercise

Background: Among growth hormone (GH) isoforms, the 22kDa (22kD) is the most abundant (~90%), followed by 20 kDa GH ((20kD) ~10%). 22kD has known diabetogenic potential by increasing insulin resistance. Although of equal somatotropic activity, 20kD has been suggested to be less diabetogenic. Under p...

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Опубликовано в: :J Endocr Soc
Главные авторы: Haenelt, Michael, Schilbach, Katharina, Gar, Christina, Longo Schweizer, Junia Ribeiro de Oliveira, Nicolay, Shiva Sophia, Andreas, Lechner, Bidlingmaier, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
Предметы:
Neuroendocrinology and Pituitary
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209317/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2305
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