SUN-LB118 Mice With Skeletal Muscle-Specific DRP1 Deficiency Are Resistant to Obesity and Diabetes Induced by a High Fat Diet

The skeletal muscle of type 2 diabetics exhibits mitochondrial dysfunction associated with increased mitochondrial fission. Dynamin-related protein 1 (DRP1) is responsible for mitochondrial division, whereas mitochondrial-endoplasmic reticulum contacts (MERCs) mark mitochondrial sites where fission...

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Bibliografske podrobnosti
izdano v:J Endocr Soc
Main Authors: Jensen, Renato Daniel, Peterson, Joshua, Allington, Benjamin, Dieter, Alayna, Cheng, Linhai, Soto, Jamie, Alambert, Renata Pereira, Correia, Marcelo, Abel, Evan Dale
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Diabetes Mellitus and Glucose Metabolism
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208802/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2320
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