SAT-583 Assessment of Thermoregulatory Pathways Induced in Male and Female Mice Lacking Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) in Response to Cold Acclimation

Pituitary Adenylate Cyclase Activating Polypetptide (PACAP) is a peptide hormone known to regulate energy homeostasis(1). Mice lacking PACAP are cold sensitive and have impaired adrenergic-induced thermogenesis(2-4). Interestingly, Pacap null mice can survive cold housing if acclimated slowly, simil...

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Vydáno v:J Endocr Soc
Hlavní autoři: Filatov, Ekaterina, Short, Landon I, Forster, Maeghan A M, Harris, Simon S, Schien, Erik N, Hughes, Malcolm C, Cline, Daemon L, Appleby, Colin J, Gray, Sarah L
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Adipose Tissue, Appetite, and Obesity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208479/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.209
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