SUN-351 Sex Is a Strong Variable in the Mineral Metabolism Defects and Endocrine Dysfunction Associated with the Murine Adenine Diet Model of Chronic Kidney Disease (CKD)

The adenine diet is widely used in animal models to produce a tubulointerstitial fibrosis and inflammation that mimics human CKD in many aspects. These include the biochemical manifestations hyperphosphatemia and anemia, as well as endocrine dysfunction with elevated FGF23 and hyperparathyroidism. M...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Liesen, Michael P, Noonan, Megan L, Clinkenbeard, Erica, Ni, Pu, Agoro, Rafiou, Tippen, Samantha P, Hum, Julia, White, Kenneth E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Bone and Mineral Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208411/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.658
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