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OR16-05 Single-Cell Sequencing Identifies Novel Regulators of Thyrotrope Populations and POU1F1-Independent Thyroid-Stimulating Hormone Expression

We implemented single-cell RNA sequencing (scRNAseq) technology as a discovery tool to identify factors enriched in differentiated thyrotropes. Thyroid-stimulating hormone (TSH) is produced in the pars distalis of the anterior pituitary (AP) and primarily acts on the thyroid gland to regulate metabo...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Autores principales: Cheung, Leonard, Daly, Alexandre, Brinkmeier, Michelle, Camper, Sally Ann
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208228/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.655
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