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SAT-426 Macro-Thyroid Stimulating Hormone (TSH) in Children

Macro-TSH is mainly a complex of TSH with anti-TSH autoantibodies. Due to its large molecular size (>150 kDa), it accumulates in the circulation resulting in elevated serum TSH concentrations. Because the bioactivity of macro-TSH is low, treatment with thyroxine is not necessary. The prevalence o...

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Bibliografische gegevens
Gepubliceerd in:J Endocr Soc
Hoofdauteurs: Hattori, Naoki, Matsuda, Takeshi, Chihara, Kazuhisa, Nishioka, Junko, Elmaoğulları, Selin, Shimatsu, Akira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208191/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.725
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