SAT-224 Recurrent Co-Driver Mutation in CTNNB1-Mutant Aldosterone-producing Adenomas (APA), Causing Reversible Hypertension in Puberty, Pregnancy or Menopause

Background: Three patients with a syndrome of LH/HCG-activated primary aldosteronism in pregnancy or menopause carrying somatic CTNNB1 mutations were reported four years ago (Teo et al. NEJM 2015). This proved but half the story. Diagnosis of an APA in a 12-year old boy with severe hypertension reve...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Autores principales: Zhou, Junhua, Cabrera, Claudia P, Azizan, Elena A B, Fernandes-Rosa, Fabio, Cottrell, Emily, Amar, Laurence, Argentesi, Giulia, Wu, Xilin, Marker, Alison, Jordan, Suzanne, Polubothu, Satyamaanasa, Berney, Daniel M, Tuthill, Antoinette, Karet, Fiona E, Metherell, Louise, Teo, Ada, Thakker, Rajesh V, Drake, William, Boulkroun, Sheerazed, Kinsler, Veronica, Storr, Helen Louise, Zennaro, Maria-Christina, Brown, Morris Jonathan
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Adrenal
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208125/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1231
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