OR05-04 Steroid Receptor Co-Activators Complexes Cooperate with Progesterone Receptors (PR) to Reprogram Metabolic Pathways that Drive Therapy Resistant Populations in ER+ Breast Cancer

Late recurrence of metastatic disease stemming from acquired therapy resistance remains a significant health burden for women with ER+ breast cancer. Disseminated ER+ tumor cell populations can remain quiescent for years to decades, and contributing factors include breast cancer stem cells (CSCs), w...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Truong, Thu H, Benner, Elizabeth, Ostrander, Julie Hanson, Lange, Carol A
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Tumor Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208123/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1307
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