SUN-017 Developmental Programming: Prenatal Testosterone Treatment Induced Metabolic Defects May Involve Premature Cellular Senescence

Prenatal exposure to excess testosterone (T) programs peripheral insulin resistance and dyslipidemia along with tissue-specific increases in ectopic lipid accumulation, oxidative stress and insulin resistance in liver and muscle of the early adult female sheep. Prenatal T increased inflammation and...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Puttabyatappa, Muraly, Ciarelli, Joseph Norman, Padmanabhan, Vasantha
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Reproductive Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207882/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1749
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