OR33-02 The Treatment of Partial Lipodystrophy in the Setting of Neutralizing Antibody Against Metreleptin with Leptin Receptor Agonist REGN4461

Background: An 18-year-old patient with atypical partial lipodystrophy had a transient initial metabolic response to metreleptin that deteriorated when neutralizing antibodies against metreleptin developed. A therapeutic trial with setmelanotide did not result in any metabolic benefit as desired. Be...

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Publicat a:J Endocr Soc
Autors principals: Akinci, Baris, de Freitas, Maria Cristina Foss, Baker, Mark, Hench, Rita, Neidert, Adam, Boutros, Sabine, Akinci, Efe Yagiz, Oral, Elif A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Adipose Tissue, Appetite, and Obesity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207664/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1072
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