OR23-04 SST5 Expression and USP8 Mutation in Functioning and Silent Corticotroph Pituitary Tumors

Context. Somatostatin receptor type 5 (SST5), a target of pasireotide, is inconsistently expressed by corticotroph tumors. Somatic driver mutations in the ubiquitin-specific protease 8 (USP8) gene have been describes in 35% to 60% of corticotropinomas. SST5 expression has been found to be higher in...

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Vydáno v:J Endocr Soc
Hlavní autoři: castellnou, Solene, Vasiljevic, Alexandre, Lapras, veronique, Raverot, Veronique, Alix, Eudeline, Borson-Chazot, Francoise, Jouanneau, Emmanuel, Lasolle, Hélene, Raverot, Gerald
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Neuroendocrinology and Pituitary
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207387/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1669
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