SUN-737 Induction of the Pro-Diabetic Gene DPP4 by Glucocorticoids: New Evidence of Pro-Inflammatory Effects in Macrophages

Glucocorticoids are potent endogenous anti-inflammatory molecules, with its receptor (GR) expressed in nearly all immune cells. Macrophages are heterogeneous cells having a central role in both tissue homeostasis and inflammation. Paradoxically glucocorticoids have a limited efficacy controlling the...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Diaz-Jimenez, David, Petrillo, Maria-Grazie, Busada, Jonathan T, Cidlowski, John A
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Steroid Hormones and Receptors
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207377/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.205
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