SUN-657 The Effect of Simvastatin on Glucose Metabolism in Primary Human Muscle Cells

Statin use, especially treatment with simvastatin, is associated with impaired insulin secretion and whole-body insulin sensitivity, and increased risk for T2D. Here, we investigated the direct effects of lactone- and acid-forms of simvastatin on glucose metabolism in primary human skeletal muscle c...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Mäkinen, Selina, Datta-Sengupta, Neeta, Nguyen, Yen, Kyrylenko, Petro, Laakso, Markku, Koistinen, Heikki A
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Diabetes Mellitus and Glucose Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207281/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1677
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