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Autophagy induction by thiostrepton improves the efficacy of immunogenic chemotherapy

BACKGROUND: Immunogenic cell death (ICD) is a peculiar modality of cellular demise that elicits adaptive immune responses and triggers T cell-dependent immunity. METHODS: Fluorescent biosensors were employed for an unbiased drug screen approach aiming at the identification of ICD enhancers. RESULTS:...

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Bibliografiske detaljer
Udgivet i:J Immunother Cancer
Main Authors: Wang, Yan, Xie, Wei, Humeau, Juliette, Chen, Guo, Liu, Peng, Pol, Jonathan, Zhang, Zhen, Kepp, Oliver, Kroemer, Guido
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206967/
https://ncbi.nlm.nih.gov/pubmed/32221018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000462
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