GLP-1 mediated diuresis and natriuresis are blunted in heart failure and restored by selective afferent renal denervation

BACKGROUND: Glucagon-like peptide-1 (GLP-1) induces diuresis and natriuresis. Previously we have shown that GLP-1 activates afferent renal nerve to increase efferent renal sympathetic nerve activity that negates the diuresis and natriuresis as a negative feedback mechanism in normal rats. However, r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cardiovasc Diabetol
Prif Awduron: Katsurada, Kenichi, Nandi, Shyam S., Zheng, Hong, Liu, Xuefei, Sharma, Neeru M., Patel, Kaushik P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Original Investigation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206815/
https://ncbi.nlm.nih.gov/pubmed/32384887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-020-01029-0
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