Propofol versus placebo (with rescue with ketamine) before less invasive surfactant administration: study protocol for a multicenter, double-blind, placebo controlled trial (PROLISA)

BACKGROUND: One major limitation for less invasive surfactant administration (LISA) is the difficulty in providing sedation before this procedure and the competitive risk of respiratory depression versus avoidance of intubation for most sedative or analgesic drugs used in this context. The objective...

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Détails bibliographiques
Publié dans:BMC Pediatr
Auteurs principaux: Chevallier, Marie, Durrmeyer, Xavier, Ego, Anne, Debillon, Thierry
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Study Protocol
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206779/
https://ncbi.nlm.nih.gov/pubmed/32384914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12887-020-02112-x
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