EAAT2 as a Research Target in Bipolar Disorder and Unipolar Depression: A Systematic Review

Glutamate is implicated in the neuropathology of both major depressive disorder and bipolar disorder. Excitatory amino acid transporter 2 (EAAT2) is the major glutamate transporter in the mammalian brain, removing glutamate from the synaptic cleft and transporting it into glia for recycling. It is t...

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Bibliographic Details
Published in:Mol Neuropsychiatry
Main Authors: Blacker, Caren J., Millischer, Vincent, Webb, Lauren M., Ho, Ada M.C., Schalling, Martin, Frye, Mark A., Veldic, Marin
Format: Artigo
Language:Inglês
Published: S. Karger AG 2020
Subjects:
Systematic Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206595/
https://ncbi.nlm.nih.gov/pubmed/32399469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000501885
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