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Long-term ex vivo expansion of mouse hematopoietic stem cells

Utilizing multipotent and self-renewing capabilities, hematopoietic stem cells (HSCs) can maintain hematopoiesis throughout life. However, the mechanism of such striking abilities remains unanswered, at least in part because of the paucity of HSCs and the modest ex vivo expansion of HSCs in medias t...

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Bibliografiske detaljer
Udgivet i:Nat Protoc
Main Authors: Wilkinson, Adam C., Ishida, Reiko, Nakauchi, Hiromitsu, Yamazaki, Satoshi
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206416/
https://ncbi.nlm.nih.gov/pubmed/31915389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-019-0263-2
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