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ER complex proteins are required for rhodopsin biosynthesis and photoreceptor survival in Drosophila and mice
Defective rhodopsin homeostasis is one of the major causes of retinal degeneration, including the disease Retinitis pigmentosa. To identify cellular factors required for the biosynthesis of rhodopsin, we performed a genome-wide genetic screen in Drosophila for mutants with reduced levels of rhodopsi...
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| 出版年: | Cell Death Differ |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206144/ https://ncbi.nlm.nih.gov/pubmed/31263175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0378-6 |
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