Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer’s disease

Amyloid-β (Aβ) oligomers largely initiate the cascade underlying the pathology of Alzheimer’s disease (AD). Galectin-3 (Gal-3), which is a member of the galectin protein family, promotes inflammatory responses and enhances the homotypic aggregation of cancer cells. Here, we examined the role and act...

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Foilsithe in:Cell Death Differ
Main Authors: Tao, Chih-Chieh, Cheng, Kuang-Min, Ma, Yun-Li, Hsu, Wei-Lun, Chen, Yan-Chu, Fuh, Jong-Ling, Lee, Wei-Ju, Chao, Chih-Chang, Lee, Eminy H. Y.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206130/
https://ncbi.nlm.nih.gov/pubmed/31127200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0348-z
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