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WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2

The activity of human paraoxonase 2 (PON2) is rapidly reduced in cells incubated with the bacterial quorormone 3-Oxo-dodecanoyl Homoserine Lactone (3OC12HSL), an observation that led to hypothesize a fast PON2 post-translational modification (PTM). Recently, we detected a 3OC12HSL-induced PTM in a c...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Carusone, Teresa Maria, Cardiero, Giovanna, Cerreta, Mariangela, Mandrich, Luigi, Moran, Oscar, Porzio, Elena, Catara, Giuliana, Lacerra, Giuseppina, Manco, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206036/
https://ncbi.nlm.nih.gov/pubmed/32382056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2504-2
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