ALDH1A3-regulated long non-coding RNA NRAD1 is a potential novel target for triple-negative breast tumors and cancer stem cells

To discover novel therapeutic targets for triple-negative breast cancer (TNBC) and cancer stem cells (CSCs), we screened long non-coding RNAs (lncRNAs) most enriched in TNBCs for high expression in CSCs defined by high Aldefluor activity and associated with worse patient outcomes. This led to the id...

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Publicat a:Cell Death Differ
Autors principals: Vidovic, Dejan, Huynh, Thomas T., Konda, Prathyusha, Dean, Cheryl, Cruickshank, Brianne M., Sultan, Mohammad, Coyle, Krysta M., Gujar, Shashi, Marcato, Paola
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206030/
https://ncbi.nlm.nih.gov/pubmed/31197235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0362-1
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