Increasing Ca(2+) in photoreceptor mitochondria alters metabolites, accelerates photoresponse recovery, and reveals adaptations to mitochondrial stress

Photoreceptors are specialized neurons that rely on Ca(2+) to regulate phototransduction and neurotransmission. Photoreceptor dysfunction and degeneration occur when intracellular Ca(2+) homeostasis is disrupted. Ca(2+) homeostasis is maintained partly by mitochondrial Ca(2+) uptake through the mito...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Hutto, Rachel A., Bisbach, Celia M., Abbas, Fatima, Brock, Daniel C., Cleghorn, Whitney M., Parker, Edward D., Bauer, Benjamin H., Ge, William, Vinberg, Frans, Hurley, James B., Brockerhoff, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206026/
https://ncbi.nlm.nih.gov/pubmed/31371786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0398-2
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