Sam50–Mic19–Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact

Mitochondrial cristae are critical for efficient oxidative phosphorylation, however, how cristae architecture is precisely organized remains largely unknown. Here, we discovered that Mic19, a core component of MICOS (mitochondrial contact site and cristae organizing system) complex, can be cleaved a...

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Publicat a:Cell Death Differ
Autors principals: Tang, Junhui, Zhang, Kuan, Dong, Jun, Yan, Chaojun, Hu, Chao, Ji, Hongchao, Chen, Liangyi, Chen, Shi, Zhao, Huabin, Song, Zhiyin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206006/
https://ncbi.nlm.nih.gov/pubmed/31097788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0345-2
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