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Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure

To maintain healthy mitochondrial enzyme content and function, mitochondria possess a complex protein quality control system, which is composed of different endogenous sets of chaperones and proteases. Heat shock protein 60 (HSP60) is one of these mitochondrial molecular chaperones and has been prop...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Fan, Feifei, Duan, Yaoyun, Yang, Feili, Trexler, Christa, Wang, Hong, Huang, Lei, Li, Yali, Tang, Huayuan, Wang, Gang, Fang, Xi, Liu, Jie, Jia, Nan, Chen, Ju, Ouyang, Kunfu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205885/
https://ncbi.nlm.nih.gov/pubmed/31209364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0374-x
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