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Ivermectin suppresses tumour growth and metastasis through degradation of PAK1 in oesophageal squamous cell carcinoma

Oesophageal squamous cell carcinoma (ESCC), the most common form of oesophageal malignancies in the Asia‐Pacific region, remains a major clinical challenge. In this study, we found that ivermectin, an effective antiparasitic drug that has been approved for patients to orally treat onchocerciasis for...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Chen, Liang, Bi, Shuning, Wei, Qiuren, Zhao, Zhijun, Wang, Chaojie, Xie, Songqiang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205794/
https://ncbi.nlm.nih.gov/pubmed/32237037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15195
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