Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells

Expansion of pulmonary neuroendocrine cells (PNECs) is a pathological feature of many human lung diseases. Human PNECs are inherently difficult to study due to their rarity (<1% of total lung cells) and a lack of established protocols for their isolation. We used induced pluripotent stem cells (i...

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Pubblicato in:iScience
Autori principali: Hor, Pooja, Punj, Vasu, Calvert, Ben A., Castaldi, Alessandra, Miller, Alyssa J., Carraro, Gianni, Stripp, Barry R., Brody, Steven L., Spence, Jason R., Ichida, Justin K., Ryan (Firth), Amy L., Borok, Zea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205764/
https://ncbi.nlm.nih.gov/pubmed/32380423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101083
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