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Identification of potassium and calcium channel inhibitors as modulators of polyomavirus endosomal trafficking

During virus entry, members of the Polyomaviridae transit the endolysosomal network en route to the endoplasmic reticulum (ER), from which degraded capsids escape into the cytoplasm and enter the nucleus. Emerging evidence suggests that viruses require both endosomal acidification and the correct io...

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Bibliografiske detaljer
Udgivet i:Antiviral Res
Main Authors: Dobson, Samuel J., Mankouri, Jamel, Whitehouse, Adrian
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205714/
https://ncbi.nlm.nih.gov/pubmed/32389733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2020.104819
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