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Identification of potassium and calcium channel inhibitors as modulators of polyomavirus endosomal trafficking

During virus entry, members of the Polyomaviridae transit the endolysosomal network en route to the endoplasmic reticulum (ER), from which degraded capsids escape into the cytoplasm and enter the nucleus. Emerging evidence suggests that viruses require both endosomal acidification and the correct io...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Dobson, Samuel J., Mankouri, Jamel, Whitehouse, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205714/
https://ncbi.nlm.nih.gov/pubmed/32389733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2020.104819
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