Altered calcium handling produces reentry-promoting action potential alternans in atrial fibrillation–remodeled hearts

Atrial fibrillation (AF) alters atrial cardiomyocyte (ACM) Ca(2+) handling, promoting ectopic beat formation. We examined the effects of AF-associated remodeling on Ca(2+)-related action potential dynamics and consequences for AF susceptibility. AF was maintained electrically in dogs by right atrial...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Liu, Tao, Xiong, Feng, Qi, Xiao-Yan, Xiao, Jiening, Villeneuve, Louis, Abu-Taha, Issam, Dobrev, Dobromir, Huang, Congxin, Nattel, Stanley
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205430/
https://ncbi.nlm.nih.gov/pubmed/32255765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133754
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