Intercalated cell BKα subunit is required for flow-induced K(+) secretion

BK channels are expressed in intercalated cells (ICs) and principal cells (PCs) in the cortical collecting duct (CCD) of the mammalian kidney and have been proposed to be responsible for flow-induced K(+) secretion (FIKS) and K(+) adaptation. To examine the IC-specific role of BK channels, we genera...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Carrisoza-Gaytan, Rolando, Ray, Evan C., Flores, Daniel, Marciszyn, Allison L., Wu, Peng, Liu, Leah, Subramanya, Arohan R., Wang, WenHui, Sheng, Shaohu, Nkashama, Lubika J., Chen, Jingxin, Jackson, Edwin K., Mutchler, Stephanie M., Heja, Szilvia, Kohan, Donald E., Satlin, Lisa M., Kleyman, Thomas R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205426/
https://ncbi.nlm.nih.gov/pubmed/32255763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130553
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