Per-6-Thiolated Cyclodextrins: A Novel Type of Permeation Enhancing Excipients for BCS Class IV Drugs

[Image: see text] The purpose of the study was to develop a per-6-thiolated α-cyclodextrin (α-CD) by substituting all primary hydroxyl groups of α-CD with thiol groups and to assess its solubility-improving and permeation-enhancing properties for a BCS Class IV drug in vitro as well as in vivo. The...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:ACS Appl Mater Interfaces
Main Authors: Asim, Mulazim Hussain, Nazir, Imran, Jalil, Aamir, Laffleur, Flavia, Matuszczak, Barbara, Bernkop-Schnürch, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205388/
https://ncbi.nlm.nih.gov/pubmed/31985207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.9b21335
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker