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Loss of Cdc13 causes genome instability by a deficiency in replication-dependent telomere capping
In budding yeast, Cdc13, Stn1, and Ten1 form the telomere-binding heterotrimer CST complex. Here we investigate the role of Cdc13/CST in maintaining genome stability by using a Chr VII disome system that can generate recombinants, chromosome loss, and enigmatic unstable chromosomes. In cells express...
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| 發表在: | PLoS Genet |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205313/ https://ncbi.nlm.nih.gov/pubmed/32287268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008733 |
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