Correcting Task fMRI Signals for Variability in Baseline CBF Improves BOLD-Behavior Relationships: A Feasibility Study in an Aging Model

Blood Oxygen Level Dependent (BOLD) functional MRI is a complex neurovascular signal whose magnitude depends on baseline physiological factors such as cerebral blood flow (CBF). Because baseline CBF varies across the brain and is altered with aging, the interpretation of stand-alone aging-related BO...

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Udgivet i:Front Neurosci
Main Authors: Krishnamurthy, Venkatagiri, Krishnamurthy, Lisa C., Drucker, Jonathan H., Kundu, Suprateek, Ji, Bing, Hortman, Kyle, Roberts, Simone R., Mammino, Kevin, Tran, Stella M., Gopinath, Kaundinya, McGregor, Keith M., Rodriguez, Amy D., Qiu, Deqiang, Crosson, Bruce, Nocera, Joe R.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205008/
https://ncbi.nlm.nih.gov/pubmed/32425745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00336
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