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Pathogenesis of Lesions Induced in Rat Lung by Chronic Tobacco Smoke Inhalation

Lesions were induced in the lungs of specific-pathogen-free F344 rats by chronic tobacco smoke exposure. Animals exposed to 7 cigarettes/day were killed after 1, 1.5, or 2 years of exposure. Parallel lifetime exposures induced pulmonary tumors in 9% of the animals. In serially killed animals, four t...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Heckman, Carol A., Dalbey, Walden E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204517/
https://ncbi.nlm.nih.gov/pubmed/6954304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/69.1.117
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