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In vivo lineage tracing of polyploid hepatocytes reveals extensive proliferation during liver regeneration

The identity of cellular populations that drive liver regeneration after injury is the subject of intense study, and the contributions of polyploid hepatocytes to organ regeneration and homeostasis have not been systematically assessed. Here we developed a multicolor reporter allele system to geneti...

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Pubblicato in:Cell Stem Cell
Autori principali: Matsumoto, Tomonori, Wakefield, Leslie, Tarlow, Branden David, Grompe, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204404/
https://ncbi.nlm.nih.gov/pubmed/31866222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.11.014
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