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The effects of combination treatments on drug resistance in chronic myeloid leukaemia: an evaluation of the tyrosine kinase inhibitors axitinib and asciminib

BACKGROUND: Chronic myeloid leukaemia is in principle a treatable malignancy but drug resistance is lowering survival. Recent drug discoveries have opened up new options for drug combinations, which is a concept used in other areas for preventing drug resistance. Two of these are (I) Axitinib, which...

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Publicat a:BMC Cancer
Autors principals: G. Lindström, H. Jonathan, Friedman, Ran
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204252/
https://ncbi.nlm.nih.gov/pubmed/32380976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06782-9
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