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Peripheral clearance of brain-derived Aβ in Alzheimer's disease: pathophysiology and therapeutic perspectives

Alzheimer’s disease (AD) is the most common type of dementia, and no disease-modifying treatments are available to halt or slow its progression. Amyloid-beta (Aβ) is suggested to play a pivotal role in the pathogenesis of AD, and clearance of Aβ from the brain becomes a main therapeutic strategy for...

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Publicat a:Transl Neurodegener
Autors principals: Cheng, Yuan, Tian, Ding-Yuan, Wang, Yan-Jiang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204069/
https://ncbi.nlm.nih.gov/pubmed/32381118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-020-00195-1
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