Nalaganje...

The contribution of large genomic rearrangements in BRCA1 and BRCA2 to South African familial breast cancer

BACKGROUND: Pathogenic variants that occur in the familial breast cancer genes (BRCA1/2) lead to truncated ineffective proteins in the majority of cases. These variants are mostly represented by small deletions/insertions, nonsense- and splice-site variants, although some larger pathogenic rearrange...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: van der Merwe, Nerina C., Oosthuizen, Jaco, Theron, Magdalena, Chong, George, Foulkes, William D.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203887/
https://ncbi.nlm.nih.gov/pubmed/32375709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06917-y
Oznake: Označite
Brez oznak, prvi označite!