Bone marrow mesenchymal stem cells improve bone erosion in collagen-induced arthritis by inhibiting osteoclasia-related factors and differentiating into chondrocytes

BACKGROUND: Rheumatoid arthritis (RA) is characterized by joint inflammation and damage to the cartilage and bone in collagen-induced arthritis (CIA). Mesenchymal stem cells (MSCs) can improve articular symptoms and reduce bone erosion in CIA rats; however, the underlying mechanism remains unknown....

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Gao, Jinfang, Zhang, Gailian, Xu, Ke, Ma, Dan, Ren, Limin, Fan, Jingjing, Hou, Jianwen, Han, Jian, Zhang, Liyun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203805/
https://ncbi.nlm.nih.gov/pubmed/32381074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01684-w
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