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Bivartect: accurate and memory-saving breakpoint detection by direct read comparison

MOTIVATION: Genetic variant calling with high-throughput sequencing data has been recognized as a useful tool for better understanding of disease mechanism and detection of potential off-target sites in genome editing. Since most of the variant calling algorithms rely on initial mapping onto a refer...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Shimmura, Keisuke, Kato, Yuki, Kawahara, Yukio
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203739/
https://ncbi.nlm.nih.gov/pubmed/31985791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa059
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