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Defining data-driven primary transcript annotations with primaryTranscriptAnnotation in R

SUMMARY: Nascent transcript measurements derived from run-on sequencing experiments are critical for the investigation of transcriptional mechanisms and regulatory networks. However, conventional mRNA gene annotations significantly differ from the boundaries of primary transcripts. New primary trans...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Anderson, Warren D, Duarte, Fabiana M, Civelek, Mete, Guertin, Michael J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203734/
https://ncbi.nlm.nih.gov/pubmed/31917388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa011
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