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Advances in biochemical and functional roles of angiotensin-converting enzyme 2 and angiotensin-(1–7) in regulation of cardiovascular function

Angiotensin-converting enzyme 2 (ACE2) is the first human homologue of ACE to be described. ACE2 is a type I integral membrane protein that functions as a carboxypeptidase, cleaving a single hydrophobic/basic residue from the COOH-terminus of its substrates. Because ACE2 efficiently hydrolyzes the p...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Ferrario, Carlos M., Trask, Aaron J., Jessup, Jewell A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203566/
https://ncbi.nlm.nih.gov/pubmed/16055515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00618.2005
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