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lncRNA AFAP1-AS1 promotes triple negative breast cancer cell proliferation and invasion via targeting miR-145 to regulate MTH1 expression

The actin fiber-associated protein 1-antisense RNA1 (AFAP1-AS1) is upregulated in various cancers and associated with cancer proliferation and metastasis. Several cancer-related pathways have been linked to up-expression of this long non-coding (lnc)RNA, but the underlying mechanisms are yet unknown...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zhang, Xiaohui, Zhou, Yidong, Mao, Feng, Lin, Yan, Shen, Songjie, Sun, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203232/
https://ncbi.nlm.nih.gov/pubmed/32376943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64713-x
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