Polarization-sensitive optical coherence tomography for estimating relative melanin content of autologous induced stem-cell derived retinal pigment epithelium

Transplantation of autologous human induced pluripotent stem cell-derived retinal pigment epithelial (hiPSC-RPE) sheets is a promising therapy for age-related macular degeneration (AMD). As melanin content is a representative feature of healthy RPE, we used polarization-sensitive optical coherence t...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Matsuzaki, Mitsuhiro, Mandai, Michiko, Yamanari, Masahiro, Totani, Kota, Nishida, Mitsuhiro, Sugita, Sunao, Maeda, Tadao, Koide, Naoshi, Takagi, Seiji, Hirami, Yasuhiko, Miyamoto, Noriko, Sugiyama, Satoshi, Takahashi, Masayo, Kurimoto, Yasuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203130/
https://ncbi.nlm.nih.gov/pubmed/32376945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64601-4
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