Leukocyte and Dried Blood Spot Arylsulfatase A Assay by Tandem Mass Spectrometry

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays were developed to measure arylsulfatase A (ARSA) activity in leukocytes and dried blood spot (DBS) using deuterated natural sulfatide substrate. These new assays were highly specific and sensitive. Patients with metachromatic leukodyst...

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Dettagli Bibliografici
Pubblicato in:Anal Chem
Autori principali: Hong, Xinying, Kumar, Arun Babu, Daiker, Jessica, Yi, Fan, Sadilek, Martin, De Mattia, Fabiola, Fumagalli, Francesca, Calbi, Valeria, Damiano, Roberta, Bona, Maria Della, la Marca, Giancarlo, Vanderver, Adeline L., Waldman, Amy T., Adang, Laura, Sherbini, Omar, Woidill, Sarah, Suhr, Teryn, Kurtzberg, Joanne, Beltran-Quintero, Maria L., Escolar, Maria, Aiuti, Alessandro, Gelb, Michael H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203001/
https://ncbi.nlm.nih.gov/pubmed/31922725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b05274
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