TRIC-A shapes oscillatory Ca(2+) signals by interaction with STIM1/Orai1 complexes

Trimeric intracellular cation (TRIC) channels have been proposed to modulate Ca(2+) release from the endoplasmic reticulum (ER) and determine oscillatory Ca(2+) signals. Here, we report that TRIC-A–mediated amplitude and frequency modulation of ryanodine receptor 2 (RyR2)-mediated Ca(2+) oscillation...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Shrestha, Niroj, Bacsa, Bernadett, Ong, Hwei Ling, Scheruebel, Susanne, Bischof, Helmut, Malli, Roland, Ambudkar, Indu Suresh, Groschner, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202670/
https://ncbi.nlm.nih.gov/pubmed/32330125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000700
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