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Broad spectrum immunomodulatory effects of Anopheles gambiae microRNAs and their use for transgenic suppression of Plasmodium

Malaria, caused by the protozoan parasite Plasmodium and transmitted by Anopheles mosquitoes, represents a major threat to human health. Plasmodium’s infection cycle in the Anopheles vector is critical for transmission of the parasite between humans. The midgut-stage bottleneck of infection is large...

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Publicado en:PLoS Pathog
Autores principales: Dong, Shengzhang, Fu, Xiaonan, Dong, Yuemei, Simões, Maria L., Zhu, Jinsong, Dimopoulos, George
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202664/
https://ncbi.nlm.nih.gov/pubmed/32330198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008453
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