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Diabetes-induced glucolipotoxicity impairs wound healing ability of adipose-derived stem cells-through the miR-1248/CITED2/HIF-1α pathway

Despite being an attractive cell type for mesenchymal stem cell (MSC) transplantation therapy for wound healing, human adipose-derived stem cells (hADSCs) from diabetes mellitus (DM) patients result in remarkable retention of stem cell activity due to diabetes-induced glucolipotoxicity. We explored...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Xiao, Shune, Zhang, Dan, Liu, Zhiyuan, Jin, Wenhu, Huang, Guangtao, Wei, Zairong, Wang, Dali, Deng, Chengliang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202540/
https://ncbi.nlm.nih.gov/pubmed/32294623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103053
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