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Sirt1 is regulated by miR-135a and involved in DNA damage repair during mouse cellular reprogramming

Sirt1 facilitates the reprogramming of mouse somatic cells into induced pluripotent stem cells (iPSCs). It is regulated by micro-RNA and reported to be a target of miR-135a. However, their relationship and roles on cellular reprogramming remain unknown. In this study, we found negative correlations...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Chen, Andy Chun Hang, Peng, Qian, Fong, Sze Wan, Yeung, William Shu Biu, Lee, Yin Lau
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202538/
https://ncbi.nlm.nih.gov/pubmed/32335545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103090
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