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Hypoxia-induced let-7f-5p/TARBP2 feedback loop regulates osteosarcoma cell proliferation and invasion by inhibiting the Wnt signaling pathway

Osteosarcoma (OS) is the most common bone tumor in children and adolescents and is characterized by high metastatic and recurrence rates. In the past, it has been shown that microRNAs may play critical roles in hypoxia-related OS proliferation and invasion. However, the mechanisms by which OS cells...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Chen, Guangnan, Gu, Huijie, Fang, Tingting, Zhou, Kaifeng, Xu, Jun, Yin, Xiaofan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202494/
https://ncbi.nlm.nih.gov/pubmed/32305960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103049
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